RESUMO
The aim of this work was to detect serologic evidence of influenza virus infections in South American fur seals (Arctocephalus australis) that inhabit the Uruguayan coast. In 29 of 37 serum samples that were analyzed, we identified antibodies to at least one of the following antigens: H1N1 (A/NewCaledonia/20/99), B/Beijing/184/93-like viruses, B/Hong Kong/330/01, and B/Sichuan/379/99 by means of the hemagglutination inhibition assay (HAI). Results confirmed that influenza A viruses circulate in marine mammals and also showed, for the first time, indirect evidence of influenza B infections in Arctocephalus australis.
Assuntos
Anticorpos Antivirais/sangue , Otárias/virologia , Vírus da Influenza A/imunologia , Vírus da Influenza B/imunologia , Animais , Feminino , Testes de Inibição da Hemaglutinação/veterinária , Masculino , Estudos Soroepidemiológicos , Uruguai/epidemiologiaRESUMO
Serologic and genetic analyses indicate that a Juquitiba-like hantavirus circulates in Maldonado, Uruguay. This virus is carried by 2 rodent species, Oligoryzomys nigripes and Oxymycterus nasutus. The same hantavirus in 2 nonrelated species can be explained by a spillover infection or a host-switching event.
Assuntos
Orthohantavírus/classificação , Orthohantavírus/isolamento & purificação , Roedores/virologia , Animais , Orthohantavírus/genética , Síndrome Pulmonar por Hantavirus/epidemiologia , Síndrome Pulmonar por Hantavirus/virologia , Filogenia , Uruguai/epidemiologiaRESUMO
During 5,230 trapping nights, 672 small mammals were trapped in the areas where most hantavirus pulmonary syndrome (HPS) cases occur in Uruguay. Yellow pygmy rice rats (Oligoryzomys flavescens) were the only rodents that showed evidence of antibodies to hantavirus, with a seroprevalence of 2.6%. The rodents were trapped in all the explored environments, and most of the seropositive rodents were found in habitats frequented by humans. Nucleotide sequences were obtained from four HPS case-patients and four yellow pygmy rice rats of the M genome segment. Sequence comparison and phylogenetic analysis showed that rodent-borne viruses and viruses from three HPS case-patients form a well-supported clade and share a 96.4% identity with the previously characterized Central Plata hantavirus. These results suggest that yellow pygmy rice rat (O. flavescens) may be the host for Central Plata, a hantavirus associated with HPS in the southern area of Uruguay.
